Kuwedzera kwehupfuuri hunoenderera mberi kuva chirwere chinokura chinobata vanhu vakuru nevana. Maererano neNational Institutes of Health, kwakave nokuwedzera nokukurumidza kwevanhu vanotambura nekuwedzeredza kana kupfuvura kwemakore makumi maviri ekupedzisira. Metabolic syndrome iri kuwedzerawo kune avo vane kuwandisa kana kuwedzera. Chirwere chemagetsi chikwata chezvipingamupinyi izvo zvinoita kuti munhu ave nechirwere chemwoyo uye chirwere.
Rubatsiro rwekuneta
Kuwedzera kwehupfumi ndezvehutano hwehutano hwepasi rese hunokurudzira kutsvakurudza kusingaperi kutsvaga nzira dzokuderedza mafuta emuviri uye zvirwere zvakabatana. Kuwedzerwa muviri uye kunyanya kuwandisa kunoratidzirwa kuti ndizvo zvikonzero zvinokonzerwa nehutachiona hwemagetsi. Tsvakurudzo yakabudiswa muNational Institutes of Health yakaratidza dhiyabhorosi inonzi isomerized (IHE), iyo inoshuva inokonzerwa nedoro kudzivirira kudya-kunokonzerwa nokuneta. Kuenderera mberi kwechikwata chechidzidzo chidzidzo chave chichitungamirirwa pamakonzo uye vanhu kuti vasimbise izvi zvakawanikwa.
Hops uye Fat Loss
Hops ndiyo inonyanya kukosha muwairi uye mushure mechikamu chechikadzi (humulus lupulus L.) . Iso-acids muhombodo inopa bheri chinhu chinotyisa. Iyo yekubika uye yekuchengetedza inogadzira chikamu chiduku chinoshungurudza chinonzi matured hop bitter acids (MHBA). MHBA inoratidzirwa kubatsira kubatsira kuderedza mafuta mumuviri mumaviri nemakwenzi.
Matured hop bitter acids (MHBA) inonzi inowedzera thermogenesis (kupisa kwekupisa) mumuviri. Kupisa kunobudiswa kubva ku thermogenesis kunoratidzwa kuti kuwedzere mafuta kupisa uye kuora kurasikirwa. MHBA yakave yakarongedzwawo kuti iwedzere mafuta (fat) oxidation muropa uye inhibitisa mafuta kubva mumatumbo. Mune mamwe mazwi, hoops inowanzopisa pane mamwe mafuta zvakasanganiswa mune chiropa uye zvinodzivirirawo kupinda mumidziyo yedu yeropa.
Hops uye Brown Fat
Tsvakurudzo yakabudiswa muNational Institutes of Health yakaongororwa matured hop bitter acids (MHBA) pamakwenzi. Chinangwa chekudzidza ndechekuratidza MHBA kunoderedza kudya-kunokonzerwa nemafuta emafuta emagetsi mumakonzo aya nemakonzo. Vatsvakurudzi vakatarisa pane mafuta anonzi brown adipose tissue (BAT) panguva yekuedzwa.
Brown adipose tissue (BAT) basa guru nderekuita muviri wekupisa. BAT ine mamwe ma-capillari uye lipidho yakaenzaniswa nemafuta machena machena. Nokuti BAT inowedzera vascular inoda oksijeni yakawanda. Mafuta eBrown anewo mitsipa isingagadzirisi inopa kukurudzira kumafuta masero. Imwe yebasa reBAT iri kutitadzisa kuti tiwedzere kuwedzera kupisa kwemuviri wedu patinotonhora. Mafuta eBrown anonziwo inhengo inoshandisa muviri inogona kugadzirisa mafuta mumuviri.
Kutsvakurudza uye Nharo
Matured hop kubvisa acids (MHBA) yakaongororwa pamakonzo anopiwa zvokudya zvakakora zvakanyanya kuti awedzere kuderedza. MBHA yakaratidza kuti inobatsira muropa kunobatsira kuderedza mafuta emuviri anowanikwa kubva pakusadya mashoma.
Pose makonzo nemakonzo zvakadzidziswa pasi pechirongwa chekliniki yakaongororwa yekuedza. Mapurati akaparadzaniswa kuva mapoka maviri ari maviri achigamuchira kudya kwemafuta akawanda (HFD). Boka rimwe rakagamuchira kutarisa kwekukura kwechingwa kuttering acids (MHBA kana MHB) kuwedzera kune HFD yavo. MHB yakawedzera zvishoma nezvishoma muboka rekutonga kwemavhiki masere. Utoro hwemuviri hwakayerwa kaviri pavhiki panguva yekuedzwa. Ropa uye miviri yemaviri zvakatorwa pamhedziso yekutongwa.
Zvitsvakurudzo zvinokonzerwa nemakonzo anopa matured hop bittering acids (MHBA kana MHB) pamwe chete neyekudya-mafuta akawanda (HFD) yakaratidza kuwanda kwemahombekombe zvakanyanya kubviswa. Zvakaratidzwawo kwaive nekuderera kwemavara e-white adipose (mafuta) uye kubviswa pachena pasina mafuta acid muropa. Zvimwe zviwanikwa zvaisanganisira kuwedzera kwevatumwa ribonucleic acid (mRNA) iyo iyo template yemaproteni synthesis (kukura) . Izvi zvinoratidza kuti MHB inokurudzira kuwedzera kweMRNA chaiyo kune thermogenesis (kupisa) kwemafuta ane maronda.
Zvitsva zvemakonzo anodya matured hop bittering acids (MHBA kana MHB) ane mishonga yakakosha-mafuta yakaratidza kukwirira kwakanyanya kwebhandi adipose tissue (BAT) uye ruremekedzo rweveural (SNA). Inoratidzwa kuti MHB inokurudzira nerve kuguma kunokurudzira thermogenesis (kupisa) kwemafuta ane maronda.
Zvose zvakaguma zvakaratidzwa matured hop bittering acids (MHBA kana MHB) sekubatsira kunobatsira kupisa mafuta ane mavara mumarangi. MHB yakaratidzwa zvakare kubatsira rubatsiro-induced body fat accumulation. Kunyange zvazvo zvidzidzo zvakawanda zvichidiwa, zvinoratidzika seMHB zvinogona kunge zvakakosha mune zvezvokudya uye zvinwiwa zve "kuderedza kudya-kunokonzerwa nemafuta ekuunganidza muviri uye kukanganiswa kwemaitiro emagetsi ."
Human Studies
Chidzidzo chakabudiswa muNutrition Journal chekuongorora kuti matanho anowedzera matuchirwe anoderedza sei mafuta emuviri muvanhu vane utano hwakanaka. Tsvakurudzo yaisanganisira mazana maviri evanhu varume nevakadzi vatori vechikamu. Vanhu vacho vaiva pakati pemakore makumi maviri nemazana makumi matanhatu nemazana matanhatu nemakore nemutumbi wemuviri (BMI) we25 kusvika ku30 kg / mami uye zvakarongedzwa mumapoka maviri. Munhu mumwe nomumwe akazvimba mudumbu reC CT kuti aenzane namazamu emimba, ropa uye urini kuongororwa sechikamu cheprotocol yekudzidza.
Panguva yekuedza kwemavhiki gumi nemaviri, zvidzidzo zvinonwa doro re 350ml rinenge rakakura rinokonzera hove (MHE) yakasanganiswa neakura hop bitter acids (MHBA) kana placebo. Zvisungo zvinoshanda uye zvisingaiti zvinotarisa uye zvakaravira zvakafanana. Zvinyorwa zvakajeka zvekudya kudya, kurovedza muviri, uye KUFUNGA kwake kwakachengetwa muchidzidzo chacho. Chero zvinetso zvehutano zvakashata zvakaonekwa zvakare.
Zvinyorwa zvitsva zveboka zvinonwa zvakadzama zvinokonzerwa nehuputi (MHE) soro yakaratidza kuderera kukuru mumimba yemuviri pamasvondo masere uye gumi nemaviri achienzaniswa nevatori venzvimbo. Sekondari migumisiro yeboka rinodya MHE raive guru rinorema kurasikirwa uye rakagadziriswa muviri mass index (BMI). Kupera kwemafuta emuviri wehuwandu hwepakati kwaive nani kune avo vanonwa MHE. Pashure pemavhiki mana, boka racho rinowedzera pamwe naMHE rakaona chiuno chakasara uye chiyero chechiyero chichienzaniswa nevatori venzvimbo yea placebo. Vanhu vakasava nemigumisiro yakaipa yakabatana newaini yekuedza munguva yekutsvakurudza.
Zvitsuwa zvekukura zvakakura (MHE) zvichibva pane zvakawanikwa, hazvina maziso epo akakwana kuti zvive nemigumisiro yekuwedzera kuneta. Vatsvakurudzi vakapedzisa hoops yakaoma acid acid (MHBA) muchirongwa chekuedza sechikamu chinokurudzira kurasikirwa kwemafuta . Tsvakurudzo yakaratidza kuti MHE yakabatana ne 35mg MHBA yakashanda mukuderedza mafuta emuviri. Zvidzidzo zvinoenderera mberi zvinodiwa asi zvinoratidzika MHE ingave "yakakosha uye yakachengeteka chidziro chekudzivirira kuneta uye kusangana kwematambudziko emagetsi."
Kunwa Bheri Kunopa Izvo Zvakanakira Here?
Kunyange zvazvo doro rine hoops yakakura uye iso-asidi makemikari, haina hutachiwana hunobatsira kuderedza dumbu remafuta . Saka, mhinduro kumubvunzo uyu ndewokuti, kwete. Kuwedzerwa kwekodhi iyi yepamusoro-koriori yekumwa mukuru inokonzerwa nekurema uye mamwe matambudziko ehutano. Uyezve, zvidzidzo zvakarongwa munyaya ino zvakarongedza kurega hops makundi akawanikwa muwairi.
Inowanikwa muFomu Rokuwedzera?
Hondo dzekukura dzakakura (MHA) dzakashandiswa mishonga kwemakore. Kutsvakurudza kunoratidza kuti MHA inobatsira seyakagadzirisa uye inoshandiswa se antibacterial. Maererano nekudzidza kwakabudiswa mu Molecular Nutrition uye Food Research, chikwata chakakura cheatac acid chinogadzirisa zvakanyanya kuvhiringidzika kwemukati. MHA inogona kutengwa seyokusagadziriswa kwemutemo kune zvinodhaka. Zvidzidzo zvekuchipatara zvichiri kuenderera mberi nehombodo dzakakura dzinoshandiswa sechinhu chinopisa mafuta kana kuti chinodzvinyirira. Tsvakurudzo dzinowanikwa dzakanaka uye inoratidzika semakemikari anoshandiswa mumapango achakurumidza kuonekwa se "kurapa nutrition therapy" achibatsira zvirwere zvisingaperi zvine chokuita nemishonga inokonzera zvirwere.
Sources:
Biomed Central, Nutrition Journal, Zvinyorwa zveMatred hop zvinoderedza mafuta mumuviri muvanhu vane hutano hwakanaka: aine maitiro akawandisa, maviri-mapofu, placebo-controlled controlled group study, Yumie Morimoto-Kobayashi et al., 2016
National Institutes of Health, Abstract, Matured Hop Kutengesa Zvikamu Induce Thermogenesis muBlack Adipose Tissue kuburikidza neSymathetic Nerve Activity, Morimoto-Kobayashi Y et al., 2015
International Journal of Obesity, Kudzivirirwa kwekudya-kunokonzerwa nokuneta nekudya zvinokonzerwa nekambani yeumusiyo ine isohumulones, mumakiritsi, Yajima H et al., 2005
National Institutes of Health, Dhipatimendi Rezvehutano Nehutano Hwevanhu, Health Topics, Chii Chinonzi Metabolic Syndrome? 6/16
Molecular Nutrition uye Research Research, Hop zvinorwadza acid inogadzirisa kuvhiringidzika pasina GRalpha, PPARalpha, kana PPARgamma, Van Cleemput M et al., 9/09