Vitamini B12 kushayikwa ndeimwe yezvakawanda zvakanyanya kushaya kukwana. Inokonzera zviratidzo zvakasiyana-siyana, zvakadai sokuneta, kukanganwa uye kumira kwemaoko nemakumbo. Chikonzero chekusiyana kwakasiyana-siyana kwezviratidzo ndeyekuti vitamini B12 inobata basa guru mumabasa mazhinji emitambo.
Vitamini B12 Chii?
Vitamini B12 ine basa rinokosha mukugadzirwa kweDNA, iyo inonzi body genetic code.
DNA inotungamirira kukodzera kwakakwana kwese chikamu chemuviri.
Vitamini B12 inoderedzawo homocysteine, imwe yemakemikari emuviri anowanzoitika. Kana homocysteine isiri yakagadziriswa zvakanaka, zvino inokonzera kuvhiringidza uye kukanganisa kwehutu mumuviri.
Zviratidzo uye Migumisiro yeVhitamin B12 Kukwana
Kupera muviri kunopera basa remasero matsvuku eropa (RBCs). Iyo hurukuro yemakiriniki ekuratidzirwa kweB12 kushayikwa inonzi megaloblastic anemia, iyo inorwara yeanemia iyo inowanzobereka kuneta uye tachycardia (kukurumidza kwemoyo wemwoyo), uye dzimwe nguva chirume. Vitamini B12 muviri unofanirwa kuti uwane masero matsvuku ekugadzirwa kweropa. MaRBC anopa okisijeni inobudisa magetsi mumuviri kuti ashandise zvose zvido zvemuviri.
Megaloblastic anemia inogona kuongororwa neropa rekuongorora.
Peripheral neuropathy rudzi rwehutano husina kunaka. Izvi zvinoreva kuti mishonga pachayo inogona kukuvadzwa kana kuti pane kushaya kweyamielin.
Myelin chifukidzo chekudzivirira chemakumbo emhepo. Vitamini B12 inobatanidza mu myelin maitiro, uye saka kushayikwa kwe vitamin B12 kunodzivirira myelin kuti asaita sezvinodiwa.
Nekushayikwa kweB12, kukanganiswa kwemisungo yakananga pamwe chete nekuderera kweeelin kunopesana nehutano hwemaitiro. Izvo zvinokonzera mitsipa zvinodzora kufamba uye kunzwa kwemuviri.
Zviratidzo zvepachirwere chirwere chepurovhesi zvinowanzokonzera tsoka uye maoko, uye zvinogona kuwedzera kusvika kune maoko nemakumbo pamwe chete. Zviratidzo zvinowanzosanganisira:
- Tingling
- Numbness
- Kushaya simba
Dementia chirwere chinoratidzirwa nekurangarira kurasika uye kuchinja maitiro. Pane zvinokonzera kukanganisa kwemararamiro, uye vitamini B12 inoshaya ndeimwe yezvikonzero zvinowanikwa munguva pfupi yapfuura. Tsvakurudzo yezvesayenzi inoratidza kuti kuora mwoyo kwemazuva ano kunokonzerwa nehutamende B12 kushayikwa kungave kwakaguma nekukwirira kwee homocysteine.
Zviratidzo zvekuora mwoyo kwemunhu zvinosanganisira:
- Kukanganwa
- Kusagutsikana
- Chinetso chokugadzirisa matambudziko
- Kusakwanisa kuisa pfungwa
- Kutadza kukwanisa kuzvitarisira iwe pachako
- Kusateerera
- Hallucinations
Kuora mwoyo ndiko kunogona kuonekwa kwevhitamisi B12, uye inogona kuendeswa neanemia kana chirwere chemangwana.
Stroke chirwere chekurapa chinoratidzwa nekudengenyeka kweropa kunopinda muuropi, zvichikonzera kushaya muviri mumuviri kana mupfungwa. Vitamini B12 kushayikwa kunogona kuwedzera njodzi yekurohwa pakati pevechidiki avo vasina kuve pangozi yekurohwa. Zvichida kana kwete pane kubatana kunopikisana zvikuru, uye njodzi inogona kuwanikwa nekuwedzera kwee homocysteine mazinga.
Myelopathy inoreva zvirwere zvomutsara wepelinha. Vitamini B12 kushayikwa kunokonzera chirwere chepinha chinonzi subacute kuputika kwechigunha chepelinha, iyo kurasikirwa kwekuchengetedza myelin kune dzimwe nzvimbo dzomutsipa wepelinha inodzora nguva, kuenzanisa uye kunzwa.
Zviratidzo zvekutsvaga kusanganiswa kwekutsvaga kwemutsipa wepelinha zvinosanganisira:
- Kushaya simba
- Unhu, kurira
- Spasticity
- Balance problems
Rurimi rwokudzora rinowanzokonzera kushayikwa kwe vitamini B12. Glossitis ndiro zita rinoshandiswa kurondedzera rurimi runorwadza, rusingawanzoitiki runogona kuguma nekukanganisika kwekudya kuno.
Mamiriro Ezvinhu Anobatana neVitamin B12 Kukwana
Chirwere chetachiona uye Multiple Sclerosis (MS) zvose zviri zviviri zvinotenderwa kuti zvine chokuita nehutachiona hwemagetsi. Chirwere chekuzvimirira chiitiko chinokonzerwa nemuviri unozvirwisa.
Izvozvo zvinokonzera kushayikwa chirwere chinokonzerwa nehurumende chinokonzerwa ne 'self' kurwisa panzvimbo yedumbu iyo inobatanidzwa mukudya kwevhitamini B12.
Kakawanda, vanhu vane chirwere chetachiona kana MS vanewo kushayikwa kwezvakakosha uye iyo inosanganiswa nemavitamini B12.
Zvinokonzera Vitamin B12 Kukwana
Low Dietary Intake
Chikonzero chinowanzovhiringidza kushaya vitamini B12 kusakwana kwevhitamini B12 mukudya. Vitamini B12 muviri unowanikwa muzvibereko zvemhuka zvakadai semhuka, huku, hove, mazai uye dairy. Saka zviputi zvinonyanya kukonzerwa nehutachiwana hwema vitamini B12, sevasiri vegan avo vasingadyi zvakakwana zvevhitamini B12 zvakakosha.
Zvimwe zvekudya zvakasimbiswa ne vitamini B12, uye kana uchida kuwana vitamini B12 yako kuburikidza nezvokudya zvevgan, unofanirwa kuedza kutsvaga iyo marudzi ezvokudya.
Kunyanya Kusarudzwa
Vitamini B12 inobatwa nemukomana muduku, asi inoda zvimwe zvokutanga kugadzirisa mudumbu pakutanga. Nokudaro, mamwe mamiriro ezvinhu anokonzera mudumbu kana musikana muduku anogona kukanganisa kukodzera kwe vitamini B12. Chinhu chinonzi intrinsic chinonzi protein inoberekwa mudumbu iyo inosanganisira vitamin B12 isati yasvika mukati memukomana muduku.
Zvirwere zvinoshandura muviri, gastric chirwere chekuvhiya nekuputika kwemudumbu yese mamiriro ezvinhu anopesana nekugadzirwa nekushanda kwechinhu chinokonzera, uye saka vitamini B12 muzvokudya haigoni kunyatsokonzerwa mumuviri, uye panzvimbo pacho, inopedzwa kuburikidza nemuviri kufamba.
Kushandisa zvakanyanya doro kunokonzera kuchinja munharaunda yemudumbu, kunopesana nekugadzirwa kwechinhu chinokonzera, zvichiita kuti B12 ishayiwe.
Utachiona hwehutachiona hwakadai seCrohn's disease uye Celiac Disease inogona kudzivirira kutora zvakakwana vitamini B12 mumatumbo maduku, zvichiita kukwana kunyange kana pane mavitamini B12 akakwana muzvokudya.
Pernicious anemia chirwere chinotapira muviri chinoderedza kana kubvisa chinokonzera, chipuroteni chiri mudumbu chinosunga zvokudya B12 kuitira kuti inogona kuiswa. Izvi zvinotungamirira kuB12 kukwana kuburikidza ne malabsorption. Izvi zvinokonzerwa neB12 hazvikwanisi kurapwa nemuromo B12, uye zvinoda kurapwa ne vitamini B12 shots.
Zviratidzo zvekushaya chirwere chinokonzera chirwere chinosanganisira:
- Kuneta
- Kusina simba
- Lightheadedness
- Kuora mwoyo
- Headaches
- Rapid moyo beat
- Kuridza munzeve
Mishonga inogona kukanganisa vitamini B12. Mishonga inowanikwa yakawanda inogona kukonzera pasi mavhitamini B12 mazinga inosanganisira:
Metformin: mushonga unoshandiswa kurapa chirwere cheshuga
Colchicine: mushonga unoshandiswa kurapa gout
Chloramphenicol: antibiotic inoshandiswa kurapa zvirwere
Mishonga yakawanda inoshandiswa mukurapa kuora mwoyo
Shoko Rinobva
Kana uine uwandu hwevhitamini B12, dzakawanda zvemigumisiro inogona kushandurwa, kunyanya pamatanho ekutanga. Kazhinji, kana kushaya simba kwako kwevhitamini B12 kunokonzerwa nekushayikwa kwezvokudya, kuwedzera kana kudya zvakagadziriswa kunogona kubatsira kuwedzera mavitamini B12 emazinga.
Kana kusagadzikana kunwa kwechikonzero ndicho chikonzero chekushaya simba kwevhitamini B12, inowanzoonekwa seinobudirira kuwana vitamini B12 yekubatsiridza kuburikidza nejojo panzvimbo pemuromo, sezvo izvi zvichibvumira kuti michero inopinda mumuviri wenyama zvakananga.
> Sources:
> Cerit L, Duygu H, Gulsen K, Kemal H, Tosun O, Ozcem B, Cerit Z, Gunsel A, Kardiol Pol. Ukama huripo pakati pevhitamini B12 uye SYNTAX chikamu. 2017; 75 (1): 65-70.
> Luciana Hannibal, Vegard Lysne, Anne-Lise Bjørke-Monsen, Sidney Behringer, Sarah C. Grünert, Ute Spiekerkoetter, Donald W. Jacobsen, uye Henk J. Blom, Biomarkers uye Maitiro Okugadzirisa Vitamini B 12 Kusakwana, Front Front Biosci. 2016; 3:27, nei: 10.3389 / fmolb.2016.00027